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WebDesethoxy quetiapine is an active metabolite of the atypical antipsychotic quetiapine (Item No. 14152).1 It is formed from quetiapine primarily by the cytochrome P450 (CYP) isoform CYP3A5 and binds to dopamine D 2 receptors (IC 50 = 1,330 nM). 1,2 Desethoxy quetiapine (20 and 40 mg/kg) reduces climbing induced by the WebBiotech Park, Phase-II, Plot - 10, Lalgadi Malakpet, Shameerpet, Turkapalli, R.R.District, Hyderabad - 500078 pheochromocytoma eye
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